Optimal target international normalized ratio for patients with mechanical heart valves
نویسندگان
چکیده
منابع مشابه
Optimal target international normalized ratio for patients with mechanical heart valves.
1. Katariya K, Yassin S, Tehrani HY, Lombardi P, Masroor S, Salerno TA. Initial experience with sutureless proximal anastomoses performed with a mechanical connector leading to clampless off-pump coronary artery bypass surgery. Ann Thorac Surg 2004;77:563–7. 2. Cavendish JJ, Penny WF, Madani MM, et al. Severe ostial saphenous vein graft disease leading to acute coronary syndromes following prox...
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BACKGROUND The optimal intensity of oral anticoagulant therapy for patients with mechanical heart valves (i.e., the level at which thromboembolic complications are effectively prevented without excessive bleeding) is not known. We attempted to determine the optimal intensity by calculating the incidence of both complications at different levels of anticoagulation. METHODS Data were collected ...
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Background and Objectives: Optimal international normalized ratio (INR) in elderly atrial fibrillation (AF) patients at higher risk of hemorrhagic events remains unclear. We investigated the efficacy and safety of low-intensity warfarin therapy (target international normalized ratio [INR], 1.6–2.6) in elderly Korean patients with nonvalvular AF (NVAF). Subjects and Methods: We enrolled 528 NVAF...
متن کاملTelemedicine-guided, very low-dose international normalized ratio self-control in patients with mechanical heart valve implants.
AIM To study in patients performing international normalized ratio (INR) self-control the efficacy and safety of an INR target range of 1.6-2.1 for aortic valve replacement (AVR) and 2.0-2.5 for mitral valve replacement (MVR) or double valve replacement (DVR). METHODS AND RESULTS In total, 1304 patients undergoing AVR, 189 undergoing MVR and 78 undergoing DVR were randomly assigned to low-dos...
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An increased risk of bleeding is associated with a more intense oral anticoagulation, a greater international normalized ratio (INR) variability and the use of aspirin. We studied the INR variability of patients (n = 121) with modern heart valves who had been prospectively randomized to receive acenocoumarol at a targeted INR of 2.4-3.6 plus aspirin 100 mg/day or acenocoumarol alone at the same...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2004
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2004.06.010